Rapid, precise quantification of large DNA excisions and inversions by ddPCR

The excision of genomic sequences using paired CRISPR-Cas nucleases is a powerful tool to study gene function, create disease models and holds promise for therapeutic gene editing. However, our understanding of the factors that favor efficient excision is limited by the lack of a rapid, accurate mea...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Watry, Hannah L., Feliciano, Carissa M., Gjoni, Ketrin, Takahashi, Gou, Miyaoka, Yuichiro, Conklin, Bruce R., Judge, Luke M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2020
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7483445/
https://ncbi.nlm.nih.gov/pubmed/32913194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-71742-z
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