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A qPCR Method for AAV Genome Titer with ddPCR-Level of Accuracy and Precision
Recombinant adeno-associated virus (rAAV) is one of the main vectors used in gene therapy. An accurate genome titer is not only critical for clinical dosing, but also a prerequisite for many analytical assays for AAV product characterization. AAV genome titer is traditionally determined by qPCR; how...
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| Publicado en: | Mol Ther Methods Clin Dev |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society of Gene & Cell Therapy
2020
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7591332/ https://ncbi.nlm.nih.gov/pubmed/33145370 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2020.09.017 |
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