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Hyperexcitability and seizures in the THY-Tau22 mouse model of Tauopathy

Epileptic seizures constitute a significant comorbidity of Alzheimer’s Disease (AD), which are recapitulated in transgenic mouse models of amyloidogenesis. Here, we sought to evaluate the potential role of Tau pathology regarding seizure occurrence. To this end, we performed intra-hippocampal electr...

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Detalhes bibliográficos
Publicado no:Neurobiol Aging
Main Authors: Gomez-Murcia, Victoria, Sandau, Ursula, Ferry, Barbara, Parrot, Sandrine, Laurent, Cyril, Basquin, Marie, Buée, Luc, Boison, Detlev, Blum, David
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7483348/
https://ncbi.nlm.nih.gov/pubmed/32679397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2020.06.004
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