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Hyperexcitability and seizures in the THY-Tau22 mouse model of Tauopathy

Epileptic seizures constitute a significant comorbidity of Alzheimer’s Disease (AD), which are recapitulated in transgenic mouse models of amyloidogenesis. Here, we sought to evaluate the potential role of Tau pathology regarding seizure occurrence. To this end, we performed intra-hippocampal electr...

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Détails bibliographiques
Publié dans:Neurobiol Aging
Auteurs principaux: Gomez-Murcia, Victoria, Sandau, Ursula, Ferry, Barbara, Parrot, Sandrine, Laurent, Cyril, Basquin, Marie, Buée, Luc, Boison, Detlev, Blum, David
Format: Artigo
Langue:Inglês
Publié: 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7483348/
https://ncbi.nlm.nih.gov/pubmed/32679397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2020.06.004
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