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Hyperexcitability and seizures in the THY-Tau22 mouse model of Tauopathy

Epileptic seizures constitute a significant comorbidity of Alzheimer’s Disease (AD), which are recapitulated in transgenic mouse models of amyloidogenesis. Here, we sought to evaluate the potential role of Tau pathology regarding seizure occurrence. To this end, we performed intra-hippocampal electr...

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Publicat a:Neurobiol Aging
Autors principals: Gomez-Murcia, Victoria, Sandau, Ursula, Ferry, Barbara, Parrot, Sandrine, Laurent, Cyril, Basquin, Marie, Buée, Luc, Boison, Detlev, Blum, David
Format: Artigo
Idioma:Inglês
Publicat: 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7483348/
https://ncbi.nlm.nih.gov/pubmed/32679397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2020.06.004
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