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Histone deacetylase 5 regulates interleukin 6 secretion and insulin action in skeletal muscle

OBJECTIVE: Physical exercise training is associated with increased glucose uptake in skeletal muscle and improved glycemic control. HDAC5, a class IIa histone deacetylase, has been shown to regulate transcription of the insulin-responsive glucose transporter GLUT4 in cultured muscle cells. In this s...

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Bibliografiske detaljer
Udgivet i:Mol Metab
Main Authors: Klymenko, Oleksiy, Brecklinghaus, Tim, Dille, Matthias, Springer, Christian, de Wendt, Christian, Altenhofen, Delsi, Binsch, Christian, Knebel, Birgit, Scheller, Jürgen, Hardt, Christopher, Herwig, Ralf, Chadt, Alexandra, Pfluger, Paul T., Al-Hasani, Hadi, Kabra, Dhiraj G.
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7481569/
https://ncbi.nlm.nih.gov/pubmed/32771698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2020.101062
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