Absence of the kinase S6k1 mimics the effect of chronic endurance exercise on glucose tolerance and muscle oxidative stress

OBJECTIVE: Ribosomal protein S6 Kinase-1 (S6K1) has been linked to resistance exercise-mediated improvements in glycemia. We hypothesized that S6K1 may also play a role in regulating glycemic control in response to endurance exercise training. METHODS: S6k1-knockout (S6K1KO) and WT mice on a 60 cal%...

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Detalhes bibliográficos
Publicado no:Mol Metab
Main Authors: Binsch, C., Jelenik, T., Pfitzer, A., Dille, M., Müller-Lühlhoff, S., Hartwig, S., Karpinski, S., Lehr, S., Kabra, D.G., Chadt, A., Roden, M., Al-Hasani, H., Castañeda, T.R.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5681242/
https://ncbi.nlm.nih.gov/pubmed/29107291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2017.08.008
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