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TLR4 Signaling by Heme and the Role of Heme-Binding Blood Proteins

Toll-like receptors (TLRs), also known as pattern recognition receptors, respond to exogenous pathogens and to intrinsic danger signals released from damaged cells and tissues. The tetrapyrrole heme has been suggested to be an agonist for TLR4, the receptor for the pro-inflammatory bacterial compone...

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Bibliografske podrobnosti
izdano v:Front Immunol
Main Authors: Janciauskiene, Sabina, Vijayan, Vijith, Immenschuh, Stephan
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7481328/
https://ncbi.nlm.nih.gov/pubmed/32983129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.01964
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