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TLR4 Signaling by Heme and the Role of Heme-Binding Blood Proteins

Toll-like receptors (TLRs), also known as pattern recognition receptors, respond to exogenous pathogens and to intrinsic danger signals released from damaged cells and tissues. The tetrapyrrole heme has been suggested to be an agonist for TLR4, the receptor for the pro-inflammatory bacterial compone...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Janciauskiene, Sabina, Vijayan, Vijith, Immenschuh, Stephan
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7481328/
https://ncbi.nlm.nih.gov/pubmed/32983129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.01964
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