Inhibition of purinergic P2X receptor 7 (P2X7R) decreases granulocyte-macrophage colony-stimulating factor (GM-CSF) expression in U251 glioblastoma cells

Glioblastoma is the most aggressive form of primary brain cancer, with a median survival of 12–15 months. The P2X receptor 7 (P2X7R) is upregulated in glioblastoma and is associated with increased tumor cell proliferation. The cytokine granulocyte-macrophage colony-stimulating factor (GM-CSF) is als...

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Publicat a:Sci Rep
Autors principals: Drill, Matthew, Powell, Kim L., Kan, Liyen Katrina, Jones, Nigel C., O’Brien, Terence J., Hamilton, John A., Monif, Mastura
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7481200/
https://ncbi.nlm.nih.gov/pubmed/32908225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-71887-x
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