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Antagonism of the ATP-gated P2X7 receptor: a potential therapeutic strategy for cancer
The P2X receptor 7 (P2X7R) is a plasma membrane receptor sensing extracellular ATP associated with a wide variety of cellular functions. It is most commonly expressed on immune cells and is highly upregulated in a number of human cancers where it can play a trophic role in tumorigenesis. Activation...
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| Publicado no: | Purinergic Signal |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer Netherlands
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8155177/ https://ncbi.nlm.nih.gov/pubmed/33728582 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11302-021-09776-9 |
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