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Antagonism of the ATP-gated P2X7 receptor: a potential therapeutic strategy for cancer

The P2X receptor 7 (P2X7R) is a plasma membrane receptor sensing extracellular ATP associated with a wide variety of cellular functions. It is most commonly expressed on immune cells and is highly upregulated in a number of human cancers where it can play a trophic role in tumorigenesis. Activation...

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Podrobná bibliografie
Vydáno v:Purinergic Signal
Hlavní autoři: Drill, Matthew, Jones, Nigel C., Hunn, Martin, O’Brien, Terence J., Monif, Mastura
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer Netherlands 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8155177/
https://ncbi.nlm.nih.gov/pubmed/33728582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11302-021-09776-9
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