Low threshold T-type calcium channels as targets for novel epilepsy treatments

Por Powell, Kim L, Cain, Stuart M, Snutch, Terrance P, O'Brien, Terence J
Publicado em 2014

Long-Term Valproate Treatment Increases Brain Neuropeptide Y Expression and Decreases Seizure Expression in a Genetic Rat Model of Absence Epilepsy

Por Elms, Johanna, Powell, Kim L., van Raay, Leena, Dedeurwaerdere, Stefanie, O’Brien, Terence J., Morris, Margaret J.
Publicado em 2013

Ethosuximide reduces epileptogenesis and behavioural comorbidity in the GAERS model of genetic generalised epilepsy

Por Dezsi, Gabi, Ozturk, Ezgi, Stanic, Davor, Powell, Kim L, Blumenfeld, Hal, O’Brien, Terence J, Jones, Nigel C
Publicado em 2013

Z944, a Novel Selective T-Type Calcium Channel Antagonist Delays the Progression of Seizures in the Amygdala Kindling Model

Por Casillas-Espinosa, Pablo Miguel, Hicks, Ashleigh, Jeffreys, Amy, Snutch, Terrance P., O’Brien, Terence J., Powell, Kim L.
Publicado no PLoS One (2015)

Interleukin-1β has trophic effects in microglia and its release is mediated by P2X7R pore

Por Monif, Mastura, Reid, Christopher A., Powell, Kim L., Drummond, Katherine J., O’Brien, Terrence J., Williams, David A.
Publicado no J Neuroinflammation (2016)

Evaluating whole genome sequence data from the Genetic Absence Epilepsy Rat from Strasbourg and its related non-epileptic strain

Por Casillas-Espinosa, Pablo M., Powell, Kim L., Zhu, Mingfu, Campbell, C. Ryan, Maia, Jessica M., Ren, Zhong, Jones, Nigel C., O’Brien, Terence J., Petrovski, Slavé
Publicado no PLoS One (2017)

Ca(V)3.2 drives sustained burst‐firing, which is critical for absence seizure propagation in reticular thalamic neurons

Por Cain, Stuart M., Tyson, John R., Choi, Hyun‐Beom, Ko, Rebecca, Lin, Paulo J. C., LeDue, Jeffrey M., Powell, Kim L., Bernier, Louis‐Philippe, Rungta, Ravi L., Yang, Yi, Cullis, Pieter R., O'Brien, Terence J., MacVicar, Brian A., Snutch, Terrance P.
Publicado no Epilepsia (2018)