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Phospho-Proteomic Discovery of Novel EPO Signal Transducers Including TXNIP as a Mediator of EPO- Dependent Human Erythropoiesis
Erythroid cell formation critically depends upon signals transduced via EPO/EPOR/JAK2 complexes. This includes not only core response modules (e.g., JAK2/STAT5, RAS/MEK/ERK), but also specialized effectors (e.g., Erythroferrone, ASCT2 glutamine transport, Spi2A). By employing phospho-proteomics and...
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| Veröffentlicht in: | Exp Hematol |
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| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7480993/ https://ncbi.nlm.nih.gov/pubmed/32259549 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2020.03.003 |
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