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Targeting EPO and EPO RECEPTOR PATHWAYS in Anemia and Dysregulated Erythropoiesis

INTRODUCTION: Recombinant human erythropoietin (rhEPO) is a first-line therapeutic for the anemia of chronic kidney disease, cancer chemotherapy, AIDS (Zidovudine therapy) and lower-risk myelodysplastic syndrome. However, rhEPO frequently elevates hypertension, is costly and may affect cancer progre...

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Detalhes bibliográficos
Publicado no:Expert Opin Ther Targets
Main Authors: Rainville, Nicole, Jachimowicz, Edward, Wojchowski, Don M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4829957/
https://ncbi.nlm.nih.gov/pubmed/26419263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/14728222.2016.1090975
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