Experimental artefacts can lead to misattribution of bioactivity from soluble mesenchymal stem cell paracrine factors to extracellular vesicles

It has been demonstrated that some commonly used Extracellular Vesicle (EV) isolation techniques can lead to substantial contamination with non-EV factors. Whilst it has been established that this impacts the identification of biomarkers, the impact on apparent EV bioactivity has not been explored....

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Bibliografische gegevens
Gepubliceerd in:J Extracell Vesicles
Hoofdauteurs: Whittaker, Thomas E., Nagelkerke, Anika, Nele, Valeria, Kauscher, Ulrike, Stevens, Molly M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Taylor & Francis 2020
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7480412/
https://ncbi.nlm.nih.gov/pubmed/32944192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/20013078.2020.1807674
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