Experimental artefacts can lead to misattribution of bioactivity from soluble mesenchymal stem cell paracrine factors to extracellular vesicles

It has been demonstrated that some commonly used Extracellular Vesicle (EV) isolation techniques can lead to substantial contamination with non-EV factors. Whilst it has been established that this impacts the identification of biomarkers, the impact on apparent EV bioactivity has not been explored....

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Bibliographic Details
Published in:J Extracell Vesicles
Main Authors: Whittaker, Thomas E., Nagelkerke, Anika, Nele, Valeria, Kauscher, Ulrike, Stevens, Molly M.
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2020
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7480412/
https://ncbi.nlm.nih.gov/pubmed/32944192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/20013078.2020.1807674
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