Experimental artefacts can lead to misattribution of bioactivity from soluble mesenchymal stem cell paracrine factors to extracellular vesicles

It has been demonstrated that some commonly used Extracellular Vesicle (EV) isolation techniques can lead to substantial contamination with non-EV factors. Whilst it has been established that this impacts the identification of biomarkers, the impact on apparent EV bioactivity has not been explored....

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Detalles Bibliográficos
Publicado en:J Extracell Vesicles
Autores principales: Whittaker, Thomas E., Nagelkerke, Anika, Nele, Valeria, Kauscher, Ulrike, Stevens, Molly M.
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis 2020
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7480412/
https://ncbi.nlm.nih.gov/pubmed/32944192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/20013078.2020.1807674
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