Experimental artefacts can lead to misattribution of bioactivity from soluble mesenchymal stem cell paracrine factors to extracellular vesicles

It has been demonstrated that some commonly used Extracellular Vesicle (EV) isolation techniques can lead to substantial contamination with non-EV factors. Whilst it has been established that this impacts the identification of biomarkers, the impact on apparent EV bioactivity has not been explored....

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Dades bibliogràfiques
Publicat a:J Extracell Vesicles
Autors principals: Whittaker, Thomas E., Nagelkerke, Anika, Nele, Valeria, Kauscher, Ulrike, Stevens, Molly M.
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2020
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7480412/
https://ncbi.nlm.nih.gov/pubmed/32944192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/20013078.2020.1807674
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