Pluripotent stem cells with low differentiation potential contain incompletely reprogrammed DNA replication

Reprogrammed pluripotent stem cells (PSCs) are valuable for research and potentially for cell replacement therapy. However, only a fraction of reprogrammed PSCs are developmentally competent. Genomic stability and accurate DNA synthesis are fundamental for cell development and critical for safety. W...

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Bibliographic Details
Published in:J Cell Biol
Main Authors: Paniza, Theodore, Deshpande, Madhura, Wang, Ning, O’Neil, Ryan, Zuccaro, Michael V., Smith, Morgan Elizabeth, Madireddy, Advaitha, James, Daylon, Ecker, Joseph, Rosenwaks, Zev, Egli, Dieter, Gerhardt, Jeannine
Format: Artigo
Language:Inglês
Published: Rockefeller University Press 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7480103/
https://ncbi.nlm.nih.gov/pubmed/32673399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201909163
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