Multiplexed chemogenetics in astrocytes and motoneurons restore blood–spinal cord barrier in ALS

Blood–spinal cord barrier (BSCB) disruption is thought to contribute to motoneuron (MN) loss in amyotrophic lateral sclerosis (ALS). It is currently unclear whether impairment of the BSCB is the cause or consequence of MN dysfunction and whether its restoration may be directly beneficial. We reveale...

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Bibliografski detalji
Izdano u:Life Sci Alliance
Glavni autori: Ouali Alami, Najwa, Tang, Linyun, Wiesner, Diana, Commisso, Barbara, Bayer, David, Weishaupt, Jochen, Dupuis, Luc, Wong, Phillip, Baumann, Bernd, Wirth, Thomas, Boeckers, Tobias M, Yilmazer-Hanke, Deniz, Ludolph, Albert, Roselli, Francesco
Format: Artigo
Jezik:Inglês
Izdano: Life Science Alliance LLC 2020
Teme:
Research Articles
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7479971/
https://ncbi.nlm.nih.gov/pubmed/32900826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.26508/lsa.201900571
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