Multiplexed chemogenetics in astrocytes and motoneurons restore blood–spinal cord barrier in ALS

Blood–spinal cord barrier (BSCB) disruption is thought to contribute to motoneuron (MN) loss in amyotrophic lateral sclerosis (ALS). It is currently unclear whether impairment of the BSCB is the cause or consequence of MN dysfunction and whether its restoration may be directly beneficial. We reveale...

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Detalhes bibliográficos
Publicado no:Life Sci Alliance
Main Authors: Ouali Alami, Najwa, Tang, Linyun, Wiesner, Diana, Commisso, Barbara, Bayer, David, Weishaupt, Jochen, Dupuis, Luc, Wong, Phillip, Baumann, Bernd, Wirth, Thomas, Boeckers, Tobias M, Yilmazer-Hanke, Deniz, Ludolph, Albert, Roselli, Francesco
Formato: Artigo
Idioma:Inglês
Publicado em: Life Science Alliance LLC 2020
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7479971/
https://ncbi.nlm.nih.gov/pubmed/32900826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.26508/lsa.201900571
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