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Generation of Nonhuman Primate Model of Cone Dysfunction through In Situ AAV-Mediated CNGB3 Ablation
A major challenge to the development of therapies for human retinal degenerative diseases is the lack of an ideal preclinical model because of the physiological differences between humans and most model animals. Despite the successful generation of a primate model through germline knockout of a dise...
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| Опубликовано в: : | Mol Ther Methods Clin Dev |
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| Главные авторы: | , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society of Gene & Cell Therapy
2020
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7479327/ https://ncbi.nlm.nih.gov/pubmed/32953936 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2020.08.007 |
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