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Generation of Nonhuman Primate Model of Cone Dysfunction through In Situ AAV-Mediated CNGB3 Ablation

A major challenge to the development of therapies for human retinal degenerative diseases is the lack of an ideal preclinical model because of the physiological differences between humans and most model animals. Despite the successful generation of a primate model through germline knockout of a dise...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Mol Ther Methods Clin Dev
Egile Nagusiak: Lin, Qiang, Lv, Ji-Neng, Wu, Kun-Chao, Zhang, Chang-Jun, Liu, Qin, Jin, Zi-Bing
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society of Gene & Cell Therapy 2020
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7479327/
https://ncbi.nlm.nih.gov/pubmed/32953936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2020.08.007
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