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Fic Proteins Inhibit the Activity of Topoisomerase IV by AMPylation in Diverse Bacteria
The Fic (filamentation induced by cyclic AMP) domain is a widely distributed motif with a conserved sequence of HPFx[D/E]GN[G/K]R, some of which regulate cellular activity by catalyzing the transfer of the AMP moiety from ATP to protein substrates. Some Fic proteins, including Fic-1 from the soil ba...
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| Publicado no: | Front Microbiol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7479194/ https://ncbi.nlm.nih.gov/pubmed/32983060 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2020.02084 |
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