VDR–SOX2 signaling promotes colorectal cancer stemness and malignancy in an acidic microenvironment

The acidic tumor microenvironment provides an energy source driving malignant tumor progression. Adaptation of cells to an acidic environment leads to the emergence of cancer stem cells. The expression of the vitamin D receptor (VDR) is closely related to the initiation and development of colorectal...

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Bibliografske podrobnosti
izdano v:Signal Transduct Target Ther
Main Authors: Hu, Pei-Shan, Li, Ting, Lin, Jin-Fei, Qiu, Miao-Zhen, Wang, De-Shen, Liu, Ze-Xian, Chen, Zhan-Hong, Yang, Lu-Ping, Zhang, Xiao-Long, Zhao, Qi, Chen, Yan-Xing, Lu, Yun-Xin, Wu, Qi-Nian, Pu, Heng-Ying, Zeng, Zhao-Lei, Xie, Dan, Ju, Huai-Qiang, Luo, Hui-Yan, Xu, Rui-Hua
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2020
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7479104/
https://ncbi.nlm.nih.gov/pubmed/32900990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41392-020-00230-7
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