Eukaryotic initiation factor 4A2 promotes experimental metastasis and oxaliplatin resistance in colorectal cancer

BACKGROUND: Deregulation of protein translation control is a hallmark of cancers. Eukaryotic initiation factor 4A2 (EIF4A2) is required for mRNA binding to ribosome and plays an important role in translation initiation. However, little is known about its functions in colorectal cancer (CRC). METHODS...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Exp Clin Cancer Res
Auteurs principaux: Chen, Zhan-Hong, Qi, Jing-Jing, Wu, Qi-Nian, Lu, Jia-Huan, Liu, Ze-Xian, Wang, Yun, Hu, Pei-Shan, Li, Ting, Lin, Jin-Fei, Wu, Xiang-Yuan, Miao, Lei, Zeng, Zhao-Lei, Xie, Dan, Ju, Huai-Qiang, Xu, Rui-Hua, Wang, Feng
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2019
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6518650/
https://ncbi.nlm.nih.gov/pubmed/31088567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-019-1178-z
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