VDR–SOX2 signaling promotes colorectal cancer stemness and malignancy in an acidic microenvironment

The acidic tumor microenvironment provides an energy source driving malignant tumor progression. Adaptation of cells to an acidic environment leads to the emergence of cancer stem cells. The expression of the vitamin D receptor (VDR) is closely related to the initiation and development of colorectal...

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Bibliografiset tiedot
Julkaisussa:Signal Transduct Target Ther
Päätekijät: Hu, Pei-Shan, Li, Ting, Lin, Jin-Fei, Qiu, Miao-Zhen, Wang, De-Shen, Liu, Ze-Xian, Chen, Zhan-Hong, Yang, Lu-Ping, Zhang, Xiao-Long, Zhao, Qi, Chen, Yan-Xing, Lu, Yun-Xin, Wu, Qi-Nian, Pu, Heng-Ying, Zeng, Zhao-Lei, Xie, Dan, Ju, Huai-Qiang, Luo, Hui-Yan, Xu, Rui-Hua
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2020
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7479104/
https://ncbi.nlm.nih.gov/pubmed/32900990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41392-020-00230-7
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