Pathologic Shear and Elongation Rates Do Not Cause Cleavage of Von Willebrand Factor by ADAMTS13 in a Purified System

INTRODUCTION: Pathological flows in patients with severe aortic stenosis are associated with acquired von Willebrand syndrome. This syndrome is characterized by excessive cleavage of von Willebrand factor by its main protease, A Disintegrin and Metalloproteinase with a Thrombospondin Type 1 Motif, M...

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Detalhes bibliográficos
Publicado no:Cell Mol Bioeng
Main Authors: Bortot, Maria, Sharifi, Alireza, Ashworth, Katrina, Walker, Faye, Cox, Allaura, Ruegg, Katherine, Clendenen, Nathan, Neeves, Keith B., Bark, David, Di Paola, Jorge
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2020
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7479076/
https://ncbi.nlm.nih.gov/pubmed/32952737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12195-020-00631-2
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