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An [(18)F]-positron emitting fluorophore allows safe evaluation of small molecule distribution in the CSF, CSF fistulas, and CNS device placement
The small molecule fluorescein is commonly used to guide the repair of cerebral spinal fluid leaks (CSFLs) in the clinic. We modified fluorescein so that it is also visible by positron emission tomography (PET). This probe was used to quantitatively track the fast distribution of small molecules in...
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| Publicat a: | Mol Pharm |
|---|---|
| Autors principals: | , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7478905/ https://ncbi.nlm.nih.gov/pubmed/31290330 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.molpharmaceut.9b00485 |
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