Uptake of exogenous serine is important to maintain sphingolipid homeostasis in Saccharomyces cerevisiae

Sphingolipids are abundant and essential molecules in eukaryotes that have crucial functions as signaling molecules and as membrane components. Sphingolipid biosynthesis starts in the endoplasmic reticulum with the condensation of serine and palmitoyl-CoA. Sphingolipid biosynthesis is highly regulat...

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Detalles Bibliográficos
Publicado en:PLoS Genet
Main Authors: Esch, Bianca M., Limar, Sergej, Bogdanowski, André, Gournas, Christos, More, Tushar, Sundag, Celine, Walter, Stefan, Heinisch, Jürgen J., Ejsing, Christer S., André, Bruno, Fröhlich, Florian
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2020
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7478846/
https://ncbi.nlm.nih.gov/pubmed/32845888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008745
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