Uptake of exogenous serine is important to maintain sphingolipid homeostasis in Saccharomyces cerevisiae

Sphingolipids are abundant and essential molecules in eukaryotes that have crucial functions as signaling molecules and as membrane components. Sphingolipid biosynthesis starts in the endoplasmic reticulum with the condensation of serine and palmitoyl-CoA. Sphingolipid biosynthesis is highly regulat...

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Publicat a:PLoS Genet
Autors principals: Esch, Bianca M., Limar, Sergej, Bogdanowski, André, Gournas, Christos, More, Tushar, Sundag, Celine, Walter, Stefan, Heinisch, Jürgen J., Ejsing, Christer S., André, Bruno, Fröhlich, Florian
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2020
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7478846/
https://ncbi.nlm.nih.gov/pubmed/32845888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008745
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