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Synaptic Vesicle Precursors and Lysosomes Are Transported by Different Mechanisms in the Axon of Mammalian Neurons

BORC is a multisubunit complex previously shown to promote coupling of mammalian lysosomes and C. elegans synaptic vesicle (SV) precursors (SVPs) to kinesins for anterograde transport of these organelles along microtubule tracks. We attempted to meld these observations into a unified model for axona...

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Bibliographische Detailangaben
Veröffentlicht in:Cell Rep
Hauptverfasser: De Pace, Raffaella, Britt, Dylan J., Mercurio, Jeffrey, Foster, Arianne M., Djavaherian, Lucas, Hoffmann, Victoria, Abebe, Daniel, Bonifacino, Juan S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7478246/
https://ncbi.nlm.nih.gov/pubmed/32553155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.107775
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