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A Mechanistic High Content Analysis Assay using Chimeric Androgen Receptor that Rapidly Characterizes Androgenic Chemicals

Human health is at risk due to environmental exposures to a wide range of chemical toxicants and endocrine disrupting chemicals (EDCs). As part of understanding this risk, the US EPA has been pursuing new high throughput in vitro assays and computational models to characterize EDCs. EPA models have...

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Detalhes bibliográficos
Publicado no:SLAS Discov
Main Authors: Szafran, AT, Bolt, MJ, Obkirchner, CE, Mancini, MG, Helsen, C, Claessens, F, Stossi, F, Mancini, MA
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7477889/
https://ncbi.nlm.nih.gov/pubmed/32392092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2472555220922917
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