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High-content screening identifies Src family kinases as potential regulators of AR-V7 expression and androgen-independent cell growth

BACKGROUND: AR-V7 is an androgen receptor (AR) splice variant that lacks the ligand-binding domain and is isolated from prostate cancer cell lines. Increased expression of AR-V7 is associated with the transition from hormone-sensitive prostate cancer to more advanced castration-resistant prostate ca...

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Detalhes bibliográficos
Publicado no:Prostate
Main Authors: Szafran, Adam T., Stephan, Cliff, Bolt, Michael, Mancini, Maureen G., Marcelli, Marco, Mancini, Michael A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5956900/
https://ncbi.nlm.nih.gov/pubmed/27699828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pros.23251
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