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Combined TLR4 and TLR9 agonists induce distinct phenotypic changes in innate immunity in vitro and in vivo

Toll-like receptor (TLR)4 and TLR9 agonists, MPL and CpG, are used as adjuvants in vaccines and have been investigated for their combined potential. However, how these two combined agonists regulate transcriptional changes in innate immune cells and cells at the site of vaccination has not been thor...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Cell Immunol
Hauptverfasser: Lampe, Anna T., Puniya, Bhanwar Lal, Pannier, Angela K., Helikar, Tomás, Brown, Deborah M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7477748/
https://ncbi.nlm.nih.gov/pubmed/32619809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellimm.2020.104149
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