A tropism-transformed Oncolytic Adenovirus with Dual Capsid Modifications for enhanced Glioblastoma Therapy

Glioblastoma, the most common human brain tumor, is highly invasive and difficult to cure using conventional cancer therapies. As an alternative, adenovirus-mediated virotherapies represent a popular and maturing technology. However, the cell surface coxsackievirus and adenovirus receptor (CAR)-depe...

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Veröffentlicht in:J Cancer
Hauptverfasser: Wang, Lizheng, Liu, Wenmo, Li, Zhe, Wang, Xupu, Feng, Xinyao, Wang, Zixuan, Wu, Jiaxin, Zhang, Haihong, Wu, Hui, Kong, Wei, Yu, Bin, Yu, Xianghui
Format: Artigo
Sprache:Inglês
Veröffentlicht: Ivyspring International Publisher 2020
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7477443/
https://ncbi.nlm.nih.gov/pubmed/32913465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.46463
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