A novel capsid-modified oncolytic recombinant adenovirus type 5 for tumor-targeting gene therapy by intravenous route

Oncolytic adenovirus (Ad)-vectored gene therapy is a promising strategy for cancer treatment. However, the lack of cancer cell selectivity or tumor tissue specificity of Ads limits their clinical application by intravenous (IV) injection. In this paper, a novel recombinant Ad5 vector was constructed...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Wang, Zhen, Yu, Bin, Wang, Baoming, Yan, Jingyi, Feng, Xiao, Wang, Zixuan, Wang, Lizheng, Zhang, Haihong, Wu, Hui, Wu, Jiaxin, Kong, Wei, Yu, Xianghui
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5216942/
https://ncbi.nlm.nih.gov/pubmed/27323824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10075
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