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Combined inhibition of JAK1/2 and DNMT1 by newly identified small-molecule compounds synergistically suppresses the survival and proliferation of cervical cancer cells

Despite substantial advances in treating cervical cancer (CC) with surgery, radiation and chemotherapy, patients with advanced CC still have poor prognosis and significantly variable clinical outcomes due to tumor recurrence and metastasis. Therefore, to develop more efficacious and specific treatme...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: She, Shiqi, Zhao, Yang, Kang, Bo, Chen, Cheng, Chen, Xinyu, Zhang, Xiaobing, Chen, Wenjie, Dan, Songsong, Wang, Hangxiang, Wang, Ying-Jie, Zhao, Jinhao
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7476923/
https://ncbi.nlm.nih.gov/pubmed/32895373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-02934-8
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