Targeting all transforming growth factor-β isoforms with an Fc chimeric receptor impairs tumor growth and angiogenesis of oral squamous cell cancer

Tumor progression is governed by various growth factors and cytokines in the tumor microenvironment (TME). Among these, transforming growth factor-β (TGF-β) is secreted by various cell types residing in the TME and promotes tumor progression by inducing the epithelial-to-mesenchymal transition (EMT)...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Takahashi, Kazuki, Akatsu, Yuichi, Podyma-Inoue, Katarzyna A., Matsumoto, Takehisa, Takahashi, Hitomi, Yoshimatsu, Yasuhiro, Koinuma, Daizo, Shirouzu, Mikako, Miyazono, Kohei, Watabe, Tetsuro
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2020
Fag:
Editors' Picks
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7476713/
https://ncbi.nlm.nih.gov/pubmed/32631954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.012492
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker