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Synthesis of (99m)Tc-labeled 2-Mercaptobenzimidazole as a novel radiotracer to diagnose tumor hypoxia

Discovery of (99m)Tc-labeled imidazole derivatives as a potential radiotracer for hypoxic tumor imaging is considered to be of great interest because of non-invasive detection capabilities. 2-Mercaptobenzimidazole (2-MBI) was successfully synthesized, characterized and radiolabeled with [(99m)Tc (CO...

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Bibliographic Details
Published in:Transl Oncol
Main Authors: Rizvi, Syed Faheem Askari, Zhang, Haixia, Mehmood, Sajid, Sanad, Mahmoud
Format: Artigo
Language:Inglês
Published: Neoplasia Press 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7475274/
https://ncbi.nlm.nih.gov/pubmed/32862104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tranon.2020.100854
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