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Coupled transmembrane mechanisms control MCU-mediated mitochondrial Ca(2+) uptake
Ca(2+) uptake by mitochondria regulates bioenergetics, apoptosis, and Ca(2+) signaling. The primary pathway for mitochondrial Ca(2+) uptake is the mitochondrial calcium uniporter (MCU), a Ca(2+)-selective ion channel in the inner mitochondrial membrane. MCU-mediated Ca(2+) uptake is driven by the si...
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| Publicado no: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7474680/ https://ncbi.nlm.nih.gov/pubmed/32801213 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2005976117 |
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