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EMRE is a Matrix Ca(2+) Sensor that Governs Gatekeeping of the Mitochondrial Ca(2+) Uniporter

The mitochondrial uniporter (MCU) is an ion channel that mediates Ca(2+) uptake into the matrix to regulate metabolism, cell death and cytoplasmic Ca(2+) signaling. Matrix Ca(2+) concentration is similar to that in cytoplasm, despite an enormous driving force for entry, but the mechanisms that preve...

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Bibliografiska uppgifter
I publikationen:Cell Rep
Huvudupphovsmän: Vais, Horia, Mallilankaraman, Karthik, Mak, Don-On Daniel, Hoff, Henry, Payne, Riley, Tanis, Jessica, Foskett, J. Kevin
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4731249/
https://ncbi.nlm.nih.gov/pubmed/26774479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.12.054
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