DUOXA1-mediated ROS production promotes cisplatin resistance by activating ATR-Chk1 pathway in ovarian cancer

The acquisition of resistance is a major obstacle to the clinical use of platinum drugs for ovarian cancer treatment. Increase of DNA damage response is one of major mechanisms contributing to platinum-resistance. However, how DNA damage response is regulated in platinum-resistant ovarian cancer cel...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Cancer Lett
Main Authors: Meng, Yunxiao, Chen, Chi-Wei, Sun, Wei, Yung, Mingo MH, Zhou, Wei, Li, Jing, Sun, Jing, Li, Zhuqing, Li, Zongzhu, Liu, Stephanie S, Cheung, Annie NY, Ngan, Hextan YS, Braisted, John C., Kai, Yan, Peng, Weiqun, Tzatsos, Alexandros, Li, Yiliang, Dai, Zhijun, Zheng, Wei, Chan, David W., Zhu, Wenge
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7474466/
https://ncbi.nlm.nih.gov/pubmed/29704517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2018.04.029
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados