Autocrine activation of JAK2 by IL-11 promotes platinum drug resistance

Antineoplastic platinum agents are used in first-line treatment of ovarian cancer, but treatment failure frequently results from platinum drug resistance. Emerging observations suggest a role of reactive oxygen species (ROS) in the resistance of cancer drugs including platinum drugs. However, the mo...

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Detalhes bibliográficos
Publicado no:Oncogene
Main Authors: Zhou, Wei, Sun, Wei, Yung, Mingo MH., Dai, Sheng, Cai, Yihua, Chen, Chi-Wei, Meng, Yunxiao, Lee, Jennifer B., Braisted, John C., Xu, Yinghua, Southall, Noel T., Shinn, Paul, Huang, Xuefeng, Song, Zhangfa, Chen, Xiulei, Kai, Yan, Cai, Xin, Li, Zongzhu, Hao, Qiang, Cheung, Annie NY., Ngan, Hextan YS., Liu, Stephanie S., Barak, Stephanie, Hao, Jing, Dai, Zhijun, Tzatsos, Alexandros, Peng, Weiqun, Pei, Huadong, Han, Zhiyong, Chan, David W., Zheng, Wei, Zhu, Wenge
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6054535/
https://ncbi.nlm.nih.gov/pubmed/29662190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-018-0238-8
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