Autocrine activation of JAK2 by IL-11 promotes platinum drug resistance

Antineoplastic platinum agents are used in first-line treatment of ovarian cancer, but treatment failure frequently results from platinum drug resistance. Emerging observations suggest a role of reactive oxygen species (ROS) in the resistance of cancer drugs including platinum drugs. However, the mo...

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Bibliografiset tiedot
Julkaisussa:Oncogene
Päätekijät: Zhou, Wei, Sun, Wei, Yung, Mingo MH., Dai, Sheng, Cai, Yihua, Chen, Chi-Wei, Meng, Yunxiao, Lee, Jennifer B., Braisted, John C., Xu, Yinghua, Southall, Noel T., Shinn, Paul, Huang, Xuefeng, Song, Zhangfa, Chen, Xiulei, Kai, Yan, Cai, Xin, Li, Zongzhu, Hao, Qiang, Cheung, Annie NY., Ngan, Hextan YS., Liu, Stephanie S., Barak, Stephanie, Hao, Jing, Dai, Zhijun, Tzatsos, Alexandros, Peng, Weiqun, Pei, Huadong, Han, Zhiyong, Chan, David W., Zheng, Wei, Zhu, Wenge
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2018
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6054535/
https://ncbi.nlm.nih.gov/pubmed/29662190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-018-0238-8
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