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MitoTEMPOL, a mitochondrial targeted antioxidant, prevents sepsis-induced diaphragm dysfunction

Clinical studies indicate that sepsis-induced diaphragm dysfunction is a major contributor to respiratory failure in mechanically ventilated patients. Currently there is no drug to treat this form of diaphragm weakness. Sepsis-induced muscle dysfunction is thought to be triggered by excessive mitoch...

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Podrobná bibliografie
Vydáno v:Am J Physiol Lung Cell Mol Physiol
Hlavní autoři: Supinski, Gerald S., Wang, Lin, Schroder, Elizabeth A., Callahan, Leigh Ann P.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7473937/
https://ncbi.nlm.nih.gov/pubmed/32460519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00473.2019
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