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Antioxidant properties of MitoTEMPOL and its hydroxylamine

Piperidine nitroxides such as TEMPOL have been widely used as antioxidants in vitro and in vivo. MitoTEMPOL is a mitochondria-targeted derivative of TEMPOL designed to protect mitochondria from the oxidative damage that they accumulate, but once there is rapidly reduced to its hydroxylamine, MitoTEM...

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Autors principals: Trnka, Jan, Blaikie, Frances H., Logan, Angela, Smith, Robin A. J., Murphy, Michael P.
Format: Artigo
Idioma:Inglês
Publicat: Informa Healthcare 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2645131/
https://ncbi.nlm.nih.gov/pubmed/19058062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10715760802582183
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