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SS31, a mitochondrially targeted antioxidant, prevents sepsis-induced reductions in diaphragm strength and endurance

Sepsis-induced diaphragm dysfunction contributes to respiratory failure and mortality in critical illness. There are no treatments for this form of diaphragm weakness. Studies show that sepsis-induced muscle dysfunction is triggered by enhanced mitochondrial free radical generation. We tested the hy...

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Detalhes bibliográficos
Publicado no:J Appl Physiol (1985)
Main Authors: Supinski, Gerald S., Wang, Lin, Schroder, Elizabeth A., Callahan, Leigh Ann P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7099438/
https://ncbi.nlm.nih.gov/pubmed/31944887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/japplphysiol.00240.2019
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