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Repertoire-scale determination of class II MHC peptide binding via yeast display improves antigen prediction

CD4(+) helper T cells contribute important functions to the immune response during pathogen infection and tumor formation by recognizing antigenic peptides presented by class II major histocompatibility complexes (MHC-II). While many computational algorithms for predicting peptide binding to MHC-II...

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Détails bibliographiques
Publié dans:Nat Commun
Auteurs principaux: Rappazzo, C. Garrett, Huisman, Brooke D., Birnbaum, Michael E.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7473865/
https://ncbi.nlm.nih.gov/pubmed/32887877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-18204-2
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