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Profiling of immune related genes silenced in EBV-positive gastric carcinoma identified novel restriction factors of human gammaherpesviruses

EBV-associated gastric cancer (EBVaGC) is characterized by high frequency of DNA methylation. In this study, we investigated how epigenetic alteration of host genome contributes to pathogenesis of EBVaGC through the analysis of transcriptomic and epigenomic datasets from NIH TCGA (The Cancer Genome...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Fiches, Guillaume N., Zhou, Dawei, Kong, Weili, Biswas, Ayan, Ahmed, Elshafa H., Baiocchi, Robert A., Zhu, Jian, Santoso, Netty
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7473590/
https://ncbi.nlm.nih.gov/pubmed/32841292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008778
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