Profiling of immune related genes silenced in EBV-positive gastric carcinoma identified novel restriction factors of human gammaherpesviruses

EBV-associated gastric cancer (EBVaGC) is characterized by high frequency of DNA methylation. In this study, we investigated how epigenetic alteration of host genome contributes to pathogenesis of EBVaGC through the analysis of transcriptomic and epigenomic datasets from NIH TCGA (The Cancer Genome...

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Vydáno v:PLoS Pathog
Hlavní autoři: Fiches, Guillaume N., Zhou, Dawei, Kong, Weili, Biswas, Ayan, Ahmed, Elshafa H., Baiocchi, Robert A., Zhu, Jian, Santoso, Netty
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2020
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7473590/
https://ncbi.nlm.nih.gov/pubmed/32841292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008778
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