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A CRISPR/Cas9 screen identifies the histone demethylase MINA53 as a novel HIV-1 latency-promoting gene (LPG)

Although combination antiretroviral therapy is potent to block active replication of HIV-1 in AIDS patients, HIV-1 persists as transcriptionally inactive proviruses in infected cells. These HIV-1 latent reservoirs remain a major obstacle for clearance of HIV-1. Investigation of host factors regulati...

詳細記述

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書誌詳細
出版年:Nucleic Acids Res
主要な著者: Huang, Huachao, Kong, Weili, Jean, Maxime, Fiches, Guillaume, Zhou, Dawei, Hayashi, Tsuyoshi, Que, Jianwen, Santoso, Netty, Zhu, Jian
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6698651/
https://ncbi.nlm.nih.gov/pubmed/31165872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz493
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